Scientist I/II, CRISPR-X (Biotech)
Job Description:
Company Overview
Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research-stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases. The Nobel Prize-winning CRISPR science has revolutionized biomedical research and represents a powerful, clinically validated approach with the potential to create a new class of potentially transformative medicines. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic partnerships with leading companies including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California, and business offices in London, United Kingdom.
Position Summary
Are you passionate about developing next-gen CRISPR therapies? We are seeking a highly motivated and creative Scientist to grow our diverse, innovation-focused CRISPR-X team that pioneers novel gene editing therapies for human disease. We are part of CRISPR Therapeutics, a leading gene editing company with a broad clinical portfolio, and research sites in Boston and San Francisco. The successful candidate will be an integral part of our team, whose aim is to research, develop and advance the next generation of genome editing modalities and genetic therapies for a wide range of human indications. The position requires enthusiasm, passion, outstanding skills in the art, attention to detail, and a desire to create new medicines for patients.
Responsibilities
- Lead, design, and optimize research with the aims of exploring and developing next-generation gene editing strategies using CRISPR-based tools and beyond.
- Design, execute, and interpret research requiring molecular biology techniques including cloning, qPCR/ddPCR, NGS, RNA and DNA analysis, cell culture, and other cell-based assays.
- Analyze and present experimental data to a wide range of audiences.
- Dissect published literature to find novel solutions to gene editing problems.
- Generate, manage, evaluate, and maintain critical data in a highly organized manner, providing statistical analysis and troubleshooting where appropriate.
Minimum Qualifications
- Prior experience with gene editing, including applying and developing next generation gene editing technologies, such as prime editing, base editing, and recombinases and retrotransposons, in an academic and/or industry setting, with a track record demonstrating significant contributions.
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Ph.D. in biology, bioengineering, or related discipline.
- Scientist I – 0-3 years of professional experience
- Scientist II – 2-5 years of professional experience
- Outstanding problem-solving skills and attitude to think outside the box.
- Expertise in molecular biology, cell culture techniques and hepatocytes.
- Excellent writing, reviewing, and presentation skills.
- Challenges oneself continuously to enhance scientific capabilities.
- Ability to work independently as well as collaboratively in a results-oriented research team environment.
- Must possess critical thinking and self-reliance to solve tasks independently.
- Self-motivated and scientifically rigorous, with outstanding organization and multitasking capability
- Entrepreneurial spirit showing resourcefulness, accountability, agility to pivot, transparency, and productivity.
Preferred Qualifications
- Prior experience with protein and/or RNA engineering.
- Prior experience with diverse delivery technologies, including transfection/nucleofection, lipid nanoparticles, and viral vectors/particles.
- Prior experience with primary hepatocytes and high-throughput screening.
Competencies
- Collaborative – Openness, One Team
- Undaunted – Fearless, Can-do attitude
- Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
- Entrepreneurial Spirit – Proactive. Ownership mindset.
Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Minimum base salary of $122,000 to a maximum base salary of $138,000 + discretionary bonus, equity and benefits.
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities. Consult with your recruiter to determine a more targeted range based on these job-related factors.
Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy
